Depends which universities you're applying to, and which sort of course you're doing. The ancient and redbrick universities (Oxford, Cambridge, Manchester, Edinburgh, the various London universities, Durham, St. Andrews) tend to show little desire for a mix of sciences and arts. If you're doing a science course, they want science A-levels. You can show how fantastic you are in art and music and history in your GCSEs.

Have fun with the booze. Take a bit of water with it every so often.


EDIT:

If you're going to do the subject, make sure you learn how to spell it correctly.